As a late effect, people who have undergone a stem cell transplant are at greater risk of developing skin cancer later in life. You will need to protect yourself against UV rays by using a sunscreen with a high sun protection factor and a hat when exposed to the sun. Being a stem cell transplant patient increases the risk of developing a secondary cancer later in life. This is due to chemotherapy, radiation therapy and other treatments you may have needed.
The biggest risk is that you will undergo the procedure and that the transplanted stem cells will not be able to delay or eliminate the disease. The cancer can come back (come back) after a stem cell transplant. However, it's less likely to happen over time. You will have daily blood tests to check the number of different types of blood cells until doctors see a steady increase in blood cell counts. In other cases, providers collect them from a donor and give them to someone who has cancerous, abnormal, or damaged stem cells (allogeneic stem cell transplant).
In previous analyses, the duration of immunosuppression (including treatment for chronic GVHD) and certain immunosuppressive drugs have been correlated with the onset of other types of cancer, especially with malignant squamous cell neoplasms. The number of survivors after successful hematopoietic stem cell (HSCT) transplantation has increased since the widespread use of HSCT in the treatment of malignant and non-malignant diseases. Sometimes, healthcare providers collect them to return to you after chemotherapy (autologous cell transplant). mother).
If you're thinking about having a stem cell transplant, talk to your healthcare provider about the potential risks and benefits. McSweeney helped develop the CAR T cell therapy program at the Colorado Blood Cancer Institute, and now focuses his research on allogeneic transplants, lymphomas and CAR T-cell therapies for malignant lymphoid neoplasms. Primary graft failure means that the transplanted stem cells have not started producing new blood cells in the first 3 to 4 weeks after the transplant. Baker hopes the study will help boost research into less toxic treatments for patients who need a blood stem cell transplant or other forms of stem cell transplantation.
The improvement in survival after hematopoietic stem cell transplantation has led to the need to evaluate long-term complications, for example, secondary malignancies. Since the first blood-producing stem cells were successfully transplanted to people with blood cancer more than 50 years ago, researchers have wondered if these cells developed cancer-causing mutations. Radiation treatments given before a stem cell transplant, chronic GVHD, infection, or the recurrence of cancer can damage brain tissue. Physicians should be aware of the high risk of secondary malignancies in patients receiving a hematopoietic stem cell transplant in later stages of life.
After a stem cell transplant, you may have access to a “late effects” clinic run by clinical nurse (CNS) specialists.
