Cona, MD, during stem cell therapy, patients usually report common symptoms with any intravenous (IV) infusion. These may include a “hurry” feeling, having to urinate more often, feeling cold or mild headache, and fatigue. Usually, patients feel tired after treatment, which can last several hours. May manifest as swollen lymph nodes, fever and chills.
There is no single standard treatment, but it is often treated by reducing the consumption of immunosuppressive drugs to allow the patient's immune system to defend itself. Other treatments include transfusions of white blood cells (lymphocytes) to stimulate the immune response, using drugs such as rituximab to kill B cells, and giving antiviral drugs to treat EBV. Your recovery after the transplant will be gradual. You probably don't feel the same way as before the illness for a while.
You may feel tired and weak, have less appetite, and notice changes in the taste and smell of things. It will also take time to regain strength and return to the activities you enjoyed before the illness and transplant. Pain at varying levels is standard in the first few days after stem cell treatment. This should become less of an issue as time goes on.
Radiation therapy and chemotherapy treatments can cause temporary or permanent infertility. This may be related to a number of factors, such as gender, age, specific type and dose of radiation or chemotherapy, and time since treatment. Graft failure is more common when the patient and donor are not well matched and when patients receive stem cells that have had their T cells removed. To increase the number of stem cells in the blood, drugs that stimulate their production will be given for about 4 days before.
If you're concerned about the effects of treatment on your ability to have children, you should discuss this with your doctor or a member of the care team before the stem cell transplant process begins.
stem cell therapy
is so new that it is almost certain that it will be the first experience for almost every patient. The goal of a stem cell transplant in cancer is to prolong life and, in many cases, even cure cancer. This is because, right after the transplant, there are not many white blood cells that work well and are the main immune cells that fight infection.The first week after an injection of regenerative cells, some people enjoy the anti-inflammatory benefit of regenerative cells, resulting in a drastic decrease in pain. If donated stem cells have been transplanted, you will usually also need to take medications that prevent the immune system from working so hard, to reduce the risk of the body attacking the transplanted cells (immunosuppressants), or to reduce the risk that the transplanted cells will attack other cells in the body. All stem cell transplant recipients experience a wide range of emotions during their recovery, some of which can be difficult to manage. For at least the first 6 weeks after the transplant, until the new stem cells begin to produce white blood cells (graft), you can easily get serious infections.
Stem Cell Transplant Complications Affecting Infections in Stem Cell Transplant Recipients, with Analogies to Patients with Hematologic Malignancies. The risk of acute GVHD can also be reduced by removing immune cells called T cells from donor stem cells before transplantation. In most cases, it develops 1 to 6 months after allogeneic stem cell transplantation, when the immune system is still very weak. After the transplant is finished, you'll need to stay in the hospital for a few weeks while you wait for the stem cells to settle in your bone marrow and start making new blood cells.
An alternative method of collecting stem cells is to remove about a liter of bone marrow from the hip bone with a needle and syringe. As transplant methods have improved, more people live longer and doctors learn more about the long-term outcomes of stem cell transplant. . .